Choroidal Effusion/Detachment Emergency An accumulation of fluid in the suprachoroidal space (between the choroid and the sclera). This can happen spontaneously but is most often a complication of eye surgery. A large effusion can cause the choroid to detach, leading to severe vision loss and pain.
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Idiopathic Polypoidal Choroidal Vasculopathy (IPCV) Serious A condition characterized by abnormal, branching networks of blood vessels with grape-like (polypoidal) tips in the choroid. It is a variant of wet AMD and can cause sudden vision loss due to bleeding or fluid leakage under the retina.
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Retinal Arterial Macroaneurysm Serious A focal outpouching or swelling of a retinal artery. These can leak fluid or blood into the retina, causing macular edema or hemorrhage, which can affect vision. They are most common in older women with high blood pressure.
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Macular Hole Serious A small, full-thickness defect in the center of the retina (the macula). It is usually caused by age-related vitreous traction on the macula. It causes a blind spot or distortion in the central vision.
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Epiretinal Membrane (Macular Pucker) Moderate A thin, scar-like tissue that forms over the surface of the macula. As this membrane contracts, it can cause the retina to wrinkle or 'pucker,' leading to distorted and blurred central vision.
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Retinitis Pigmentosa (RP) Serious A group of inherited genetic disorders that affect the retina's ability to respond to light. It causes a slow but progressive loss of vision, starting with night blindness and loss of peripheral vision, eventually leading to 'tunnel vision' and sometimes total blindness.
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Inherited Chorioretinal Dystrophies Serious A broad category of genetic diseases that cause progressive degeneration of the retina and/or choroid. This group includes conditions like choroideremia, gyrate atrophy, and various pattern dystrophies, each with unique features and inheritance patterns.
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Cone Dystrophies Serious A group of inherited retinal disorders that affect the cone cells, which are responsible for central and color vision. This leads to a progressive decline in visual acuity, severe light sensitivity, and loss of color vision.
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Stargardt Disease (Fundus Flavimaculatus) Serious The most common form of inherited juvenile macular degeneration. It's an autosomal recessive condition that causes progressive central vision loss from the death of photoreceptor cells in the macula. It typically starts in childhood or adolescence.
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Best Disease (Vitelliform Macular Dystrophy) Serious An inherited retinal dystrophy characterized by the formation of a yellow, egg yolk-like lesion in the macula. While vision can be good for many years, it can eventually lead to central vision loss when the lesion breaks up or if choroidal neovascularization develops.
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Chloroquine / Hydroxychloroquine Toxicity Serious Retinal damage that can occur from long-term use of the medications chloroquine (Aralen) and hydroxychloroquine (Plaquenil), which are used to treat autoimmune diseases like rheumatoid arthritis and lupus. The toxicity can cause irreversible central vision loss.
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Crystalline Retinopathy Moderate A condition characterized by the presence of small, shiny, refractile deposits within the retina. This can be caused by certain medications (e.g., tamoxifen, canthaxanthin), metabolic diseases (e.g., Bietti's crystalline dystrophy), or be idiopathic.
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Optic Pit Serious A congenital defect of the optic nerve head, appearing as a small, gray-white depression. While often stable, optic pits are associated with a risk of fluid from the vitreous cavity seeping under the retina, causing a serous macular detachment.
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Solar Retinopathy Moderate Damage to the retina, particularly the macula, from looking directly at the sun (sun gazing). This photochemical damage can cause a permanent small blind spot in the central vision.
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Choroidal Nevus Mild A choroidal nevus is a common, benign, pigmented lesion in the choroid, similar to a mole on the skin. While most are harmless, there is a very small risk that they can transform into a malignant melanoma.
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Malignant Melanoma of the Choroid Emergency The most common primary intraocular malignancy in adults. It is a cancerous tumor arising from the pigment cells (melanocytes) of the choroid. It can spread (metastasize) to other parts of the body, most commonly the liver.
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Nonexudative (Dry) Age-Related Macular Degeneration Serious The most common form of AMD, characterized by the presence of drusen (yellow deposits) under the retina and thinning of the macula (atrophy). It leads to a slow, progressive decline in central vision.
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Macular Degeneration Serious Age-Related Macular Degeneration (AMD) is a leading cause of vision loss in people over 50. It damages the macula, the part of the retina responsible for sharp, central vision. There are two main types: Dry AMD (more common, slower progression) and Wet AMD (less common, but more severe and rapid).
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