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Limbal Stem Cell Deficiency: Symptoms, Causes & Treatment in Orange CountyExpert Eye Care from Orange County’s Leading Specialists

Expert information about limbal stem cell deficiency from Orange County's leading eye care specialists. Learn about symptoms, causes, diagnosis, and the latest treatment options.

Medically reviewed by Dr. Alexander Bonakdar, O.D. · Updated April 2026

What is Limbal Stem Cell Deficiency?

Limbal stem cell deficiency (LSCD) occurs when the stem cells at the border of the cornea and sclera (the limbus) are destroyed or depleted. These stem cells are responsible for continuously regenerating the corneal epithelium. Without them, the conjunctival tissue grows over the cornea (conjunctivalization), causing vascularization, chronic inflammation, persistent epithelial defects, and progressive vision loss. Causes include chemical burns, Stevens-Johnson syndrome, chronic contact lens wear, radiation, and autoimmune conditions. Scleral lenses provide a protective environment that supports remaining stem cells.

At EyeCare Center of Orange County, we specialize in the diagnosis and treatment of limbal stem cell deficiency. Our experienced optometrists use state-of-the-art technology to provide comprehensive care and help preserve your vision.

Common Symptoms of Limbal Stem Cell Deficiency

If you're experiencing any of these symptoms, schedule a comprehensive eye examination:

Progressive corneal haze or opacification

Chronic redness and inflammation

Recurrent or persistent corneal erosions

Vascularization growing onto the cornea

Pain and light sensitivity

Vision loss that progressively worsens

Treatment Options for Limbal Stem Cell Deficiency

We offer comprehensive treatment options tailored to your specific needs:

Scleral Contact Lens Fitting

Limbal Stem Cell Transplant (LSCT)

Amniotic Membrane Transplant

Autologous Serum Eye Drops

Corneal Transplant (after stem cell restoration)

Anti-inflammatory Therapy

Why Choose EyeCare Center of Orange County?

Over 30 Years of Experience

Dr. Alexander Bonakdar has been serving Orange County since 1991 with specialized expertise in ocular surface disease.

Advanced Diagnostic Technology

We utilize the latest equipment for accurate diagnosis and effective treatment of limbal stem cell deficiency.

Personalized Treatment Plans

Every patient receives customized care based on their unique needs and condition severity.

Comprehensive Eye Care

From diagnosis to treatment and follow-up care, we provide complete support throughout your treatment journey.

Frequently Asked Questions

What causes limbal stem cell deficiency?

The most common causes are chemical/thermal burns, Stevens-Johnson syndrome, chronic contact lens overwear, radiation therapy, severe ocular surface infections, and autoimmune conditions like ocular cicatricial pemphigoid. Some cases are congenital (aniridia-associated LSCD).

Does insurance cover Limbal Stem Cell Deficiency treatment?

Most vision and medical insurance plans cover diagnostic exams and medically necessary treatments. We accept most major insurance plans and can help verify your coverage before treatment.

Don't Let Limbal Stem Cell Deficiency Impact Your Vision

Schedule your comprehensive eye examination today and get expert diagnosis and treatment.

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